Streetwise snake-catcher Simon Keys and his sassy herpetologist girlfriend, Siouxsie Gillett, rush around Snake City to save snakes that have ventured into human territory. They hunt down a frighteningly fast black mamba in a cluttered kitchen, and a Mozambique spitting cobra under a bath that's showering Simon with venom. All before he has to face his irrational fear of heights while trying to retrieve a green mamba from a tree.