Deep in Alaska, the primal way lives on. Fight the freeze, brave the wild, hold on to your sanity. And winter is no wonderland when temperatures plummet far below zero. This series follows the drama and hardships experienced by Alaskan households in different corners of this merciless territory as they battle to survive, thrive, and live life on their own terms.

Ben Fogle travels round the world to visit people who have given up the rat race.

Michael Mosley finds out why fizzy drinks make you eat more, Dr Zoe Williams investigates whether caffeine boosts your physical performance, and surgeon Gabriel Weston looks into the new artificial pancreas that could transform life for diabetics.

Can they face their fears? Celebrities take on epic adventures and freezing temperatures with Iceman Wim Hof. He'll push their minds to the limit - will he change their lives?